sharing methods for global health research an assessment of methodology CORD-Papers-2022-06-02 (Version 1)

Title: Sharing methods for global health research: an assessment of methodology
Abstract: Abstract Background Setting up a clinical study can take more than 18 months and can cost millions of pounds. For many aspects of global health there is a dearth of research yet evidence is urgently needed to address major challenges. Obtaining such data within a meaningful timeframe requires a fundamental change in the planning and setting up of research studies. Typically protocols are developed in closed groups and often never shared. However many operational processes in research are generic irrespective of the disease or design. Thus removal of duplication and sharing methods could speed up research. This research methodology project investigates whether researchers can be persuaded to share methods and if this will streamline research. Methods The theory of communities of practice (in which distinct specialists working on a problem collaborate to solve it) guided this project. The Global Health Network was created to enable communities of practice to form to develop protocols exchange research instruments and share skills. We measured uptake effect and benefit of the Network through surveys questionnaires interviews with target audiences (research teams in low-income and middle-income countries) and analysis of digital access. Findings Since 2011 more than 60 000 researchers nurses technicians and scientists from almost all low-income and middle-income countries have used the project to share research methods knowledge and processes. 21 specialised communities of practice have formed collaborations that are actively exchanging methods. More than 250 research guidance notes have been shared that provide specific guidance for various research methodseg an international respiratory disease network has released three open-access novel coronavirus protocols and groups working in maternal health are listing the samples they have stored with the invitation for others to collaborate. These qualitative and quantitative data show that these exchanges are highly beneficial for guiding and improving research operations and that there is a willingness to share. Interpretation Scientists compete for funding and publication and therefore sharing methods and knowledge can be perceived as disadvantageous. However if use of protocols and methods developed by wide and open consensus can help to quickly gain high quality data then better progress could be made for all and disease research could be changed to improve health. Funding Bill & Melinda Gates Foundation.
Published: 2013-10-20
Journal: The Lancet
DOI: 10.1016/s0140-6736(13)62166-2
DOI_URL: http://doi.org/10.1016/s0140-6736(13)62166-2
Author Name: Lang Trudie
Author link: https://covid19-data.nist.gov/pid/rest/local/author/lang_trudie
Author Name: Marsh Kevin
Author link: https://covid19-data.nist.gov/pid/rest/local/author/marsh_kevin
Author Name: Peeling Rosanna
Author link: https://covid19-data.nist.gov/pid/rest/local/author/peeling_rosanna
Author Name: Farrar Jeremy
Author link: https://covid19-data.nist.gov/pid/rest/local/author/farrar_jeremy
license: els-covid
license_url: https://www.elsevier.com/about/policies/open-access-licenses/elsevier-user-license
source_x: Elsevier; PMC
source_x_url: https://www.elsevier.com/https://www.ncbi.nlm.nih.gov/pubmed/
pubmed_id: 23683601
pubmed_id_url: https://www.ncbi.nlm.nih.gov/pubmed/23683601
pmcid: PMC7155427
pmcid_url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155427
url: https://www.sciencedirect.com/science/article/pii/S0140673613621662 https://api.elsevier.com/content/article/pii/S0140673613621662
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G_ID: sharing_methods_for_global_health_research_an_assessment_of_methodology