sex differences in patients with covid 19 a retrospective cohort study and meta analysis CORD-Papers-2021-10-25 (Version 1)

Title: Sex differences in patients with covid-19: A retrospective cohort study and meta-analysis
Abstract: BACKGROUND: Accumulated evidence revealed that male was much more likely to higher severity and fatality by SARS-CoV-2 infection than female patients, but few studies and meta-analyses have evaluated the sex differences of the infection and progression of COVID-19 patients AIM: We aimed to compare the sex differences of the epidemiological and clinical characteristics in COVID-19 patients;and to perform a meta-analysis evaluating the severe rate, fatality rate, and the sex differences of the infection and disease progression in COVID-19 patients METHODS: We analyzed clinical data of patients in Changchun Infectious Hospital and Center, Changchun, Northeast China;and searched PubMed, Embase, Web of Science, and Cochrane Library without any language restrictions for published articles that reported the data of sex-disaggregated, number of severe, and death patients on the confirmed diagnosis of adult COVID-19 patients RESULTS: The pooled severe rate and fatality rate of COVID-19 were 22 7% and 10 7% Male incidence in the retrospective study was 58 1%, and the pooled incidence in male was 54 7% CONCLUSION: The pooled severe rate in male and female of COVID-19 was 28 2% and 18 8%, the risky of severe and death was about 1 6folds higher in male compared with female, especially for older patients (> 50 y) 2020 Zhijun Li, Lina Feng, Wenyu Cui, Jian Zhang, Yingxin Huang, Yunhong Zhao, Fei Teng, Donglin Wu, Bonan Cao, Hui Wang, Liquan Deng, Qiong Yu
Published: 2020
Journal: Open Access Macedonian Journal of Medical Sciences
Author Name: Li, Z
Author link: https://covid19-data.nist.gov/pid/rest/local/author/li_z
Author Name: Feng, L
Author link: https://covid19-data.nist.gov/pid/rest/local/author/feng_l
Author Name: Cui, W
Author link: https://covid19-data.nist.gov/pid/rest/local/author/cui_w
Author Name: Zhang, J
Author link: https://covid19-data.nist.gov/pid/rest/local/author/zhang_j
Author Name: Huang, Y
Author link: https://covid19-data.nist.gov/pid/rest/local/author/huang_y
Author Name: Zhao, Y
Author link: https://covid19-data.nist.gov/pid/rest/local/author/zhao_y
Author Name: Teng, F
Author link: https://covid19-data.nist.gov/pid/rest/local/author/teng_f
Author Name: Wu, D
Author link: https://covid19-data.nist.gov/pid/rest/local/author/wu_d
Author Name: Cao, B
Author link: https://covid19-data.nist.gov/pid/rest/local/author/cao_b
Author Name: Wang, H
Author link: https://covid19-data.nist.gov/pid/rest/local/author/wang_h
Author Name: Deng, L
Author link: https://covid19-data.nist.gov/pid/rest/local/author/deng_l
Author Name: Yu, Q
Author link: https://covid19-data.nist.gov/pid/rest/local/author/yu_q
license: unk
license_url: [unknown license]
source_x: WHO
source_x_url: https://www.who.int/
who_covidence_id: #1082569
has_full_text: FALSE
G_ID: sex_differences_in_patients_with_covid_19_a_retrospective_cohort_study_and_meta_analysis
S2 ID: 234545876