microscopic transsphenoidal approach for macroadenoma in an asymptomatic covid 19 CORD-Papers-2021-10-25 (Version 1)

Title: Microscopic transsphenoidal approach for macroadenoma in an asymptomatic COVID-19 patient: A case report
Abstract: The novel coronavirus commonly referred to as COVID-19 became a global pandemic in the March of 2020 and createdunprecedented challenges for health care systems worldwide. Early case reports demonstrated a high risk of aerosolizationand infection of operating room staff during endoscopic endonasal approaches, highlighting the need for safe managementstrategies in patients with COVID-19 with acute pathology. During periods of epidemiologic infectious surges, elective caseshave often been suspended. However, patients presenting with urgent pathology, such as pituitary apoplexy or acute visualcompromise from sellar or parasellar lesions still require treatment regardless of infectious status. Here, we present a caseof an asymptomatic COVID-19 patient with progressive vision loss that underwent successful microscopic resection ofpituitary adenoma, without evidence of spread to the operating room staff. We hypothesize that during microscopicapproaches to the sella, there is relatively less forceful irrigation, and as a result, potentially less aerosolization. This maydecrease the risk of viral spread to the surgeons and the operating room staff. Additionally, we report that fluorescent insitu hybridization studies of tumor tissue for SARS-CoV-2 may not reliably be able to detect viral infections. In conclusion,for asymptomatic patients at high risk for COVID, microscopic transsphenoidal approaches may provide a safer alternative.These patients should undergo preoperative testing, and repeat testing should be considered if possible for negative results.Proper PPE should however still be utilized to maximize safety of the operating room staff.
Published: 2021
Journal: Journal of Neurological Surgery Part B: Skull Base
Author Name: Higgins, D
Author link: https://covid19-data.nist.gov/pid/rest/local/author/higgins_d
Author Name: Upadhyayula, P
Author link: https://covid19-data.nist.gov/pid/rest/local/author/upadhyayula_p
Author Name: Liu, Y
Author link: https://covid19-data.nist.gov/pid/rest/local/author/liu_y
Author Name: Delgardo, M
Author link: https://covid19-data.nist.gov/pid/rest/local/author/delgardo_m
Author Name: Dalahmah, O A
Author link: https://covid19-data.nist.gov/pid/rest/local/author/dalahmah_o_a
Author Name: Canoll, P
Author link: https://covid19-data.nist.gov/pid/rest/local/author/canoll_p
Author Name: Bruce, J
Author link: https://covid19-data.nist.gov/pid/rest/local/author/bruce_j
license: unk
license_url: [unknown license]
source_x: WHO
source_x_url: https://www.who.int/
who_covidence_id: #covidwho-1254097
has_full_text: FALSE
G_ID: microscopic_transsphenoidal_approach_for_macroadenoma_in_an_asymptomatic_covid_19
S2 ID: 234903162