association between eczema and major cardiovascular outcomes in population based studies CORD-Papers-2022-06-02 (Version 1)

Title: Association between eczema and major cardiovascular outcomes in population-based studies: a systematic review protocol.
Abstract: INTRODUCTION Chronic inflammatory diseases such as eczema (also known as atopic dermatitis) have been inconsistently linked to cardiovascular disease and stroke in both mechanistic and epidemiological studies. There is a need to review the existing epidemiological data examining the association between eczema and major cardiovascular outcomes including angina myocardial infarction coronary revascularisation heart failure cardiac arrhythmias stroke and cardiovascular death in order to improve our understanding of the comorbidities of eczema. METHODS AND ANALYSIS We will systematically review population-based studies including cohort case-control and cross-sectional studies reporting on the association between eczema and cardiovascular outcomes. We will search Medline Embase and Global Health from their date of inception to April 2017 using a comprehensive search strategy formulated with the help of a librarian. Two reviewers will independently screen titles and abstracts in duplicate followed by independent data extraction and quality assessment. We will group studies by the cardiovascular outcome under study and synthesise them narratively. If sufficient numbers of homogeneous studies are returned we will perform meta-analyses to obtain pooled effect estimates. Preferred Reporting Items for Systematic Review and Meta-Analysis will be used to inform the reporting of this study. TRIAL REGISTRATION NUMBER CRD42017060359.
Published: 2017
Journal: BMJ open
DOI: 10.1136/bmjopen-2017-017979
Author Name: Ascott Anna
Author link:
Author Name: Yu Ashley M
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Author Name: Schmidt Morten
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Author Name: Abuabara Katrina
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Author Name: Smeeth Liam
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Author Name: Langan Sinad M
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license: cc-by
source_x: Medline
pubmed_id: 28965102
has_full_text: FALSE
G_ID: association_between_eczema_and_major_cardiovascular_outcomes_in_population_based_studies